Percy Lavon Julian was an American research
chemist and a pioneer in the
chemical synthesis of medicinal
drugs from plants. He was the first to synthesize the natural product
physostigmine, and a pioneer in the industrial large-scale chemical synthesis of the human hormones
progesterone and
testosterone from
plant sterols such as
stigmasterol and sitosterol. His work laid the foundation for the
steroid drug industry's production of
cortisone, other
corticosteroids, and
birth control pills. He later started his own company to synthesize steroid intermediates from the wild
Mexican yam. His work helped greatly reduce the cost of steroid intermediates to large multinational pharmaceutical companies, helping to significantly expand the use of several important drugs. Julian received more than 130 chemical patents. He was one of the first
African-Americans to receive a doctorate in
chemistry. He was the first African-American
chemist inducted into the
National Academy of Sciences, and the second African-American scientist inducted (behind
David Blackwell) from any field.
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